Pharmacy Technician Practice Test 2026

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🎯 Practice by Topic

Drug Names, Classes & Indications

PTCE Domain 1 (part) — generic and brand names, drug classifications and what each class treats, indications of common medications, and therapeutic duplications.

60 questions→

Dosing, Interactions, Side Effects, Storage & Stability

PTCE Domain 1 (part) — strengths, doses, dosage forms and routes of administration; drug interactions and contraindications; side/adverse effects and allergies; drug stability; and proper storage (temperature, light, restricted access).

60 questions→

Federal Requirements & DEA Controlled Substances

PTCE Domain 2 (18.75%) — federal storage/handling/disposal of hazardous and non-hazardous substances; DEA controlled-substance schedules (C-I to C-V), prescriptions, refills, ordering (DEA Form 222/CSOS), loss/theft and destruction; restricted-drug programs (pseudoephedrine, REMS); FDA recalls; and DSCSA serialization/tracing.

55 questions→

Patient Safety & Quality Assurance

PTCE Domain 3 (23.75%) — high-alert and look-alike/sound-alike (LASA) medications; error-prevention strategies (Tall Man lettering, leading zeros / no trailing zeros, bar codes, avoiding error-prone abbreviations); issues requiring pharmacist intervention (DUR, ADE); event reporting (MedWatch, VAERS, RCA); types of prescription errors; and infection prevention.

55 questions→

Pharmacy Calculations & Sig Codes

PTCE Domain 4 (part) — pharmacy calculations: ratios and proportions, percentage strength, dilution (C1V1 = C2V2), alligation, days supply, weight-based (mg/kg) dosing, IV flow rate, and unit conversions; plus Sig codes, Roman numerals, and common pharmacy abbreviations. Each calculation is shown step by step.

50 questions→

Order Entry, Equipment, NDC & Inventory

PTCE Domain 4 (part) — equipment and supplies for drug administration; lot numbers, expiration/beyond-use dates, and National Drug Code (NDC) numbers; and procedures for identifying and returning dispensable, non-dispensable, and expired medications (return to stock, reverse distribution).

40 questions→

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